Ph.D. Student Publications and Presentations (student’s name in bold)

2015 Published Work

Benedetto, G. Hamp, T.J., Wesselman, P.J., Richardson, C.  (2015) Identification of epithelial ovarian tumor specific aptamers. Nucleic Acid Therapeutics.

Felt, S.A., Moerdyk-Schauwecker,M.J., Grdzelishvili, V.Z. (2015) Induction of apoptosis in pancreatic ductal adenocarcinoma cells by vesicular stomatitis virus. Virology.

Oral Presentations

Sombatsaphay, V., and Reitzel, A.M. Phylogenetic diversity, developmental expression and salinity induced expression of aquaporins in the estuarine anemone Nematostella vectensis. Presented at Society for Integrative and Comparative Biology Meeting, Jan 2015.

Poster Presentations

Wang, L., Lim, C.K., Klotz, M. Gene expression of hao affects the molecular basis of nitrogen transformations in Methylococcus capsulatus Bath, a nitrifying methanotroph. Presented at the 2nd Annual Southeastern Biogeochemistry Symposium, March 2015.

2014 Published Work

Hastie, Eric, Besmer, DM, Shah, NR, Murphy, AM, Moerdyk-Schauwecker, M, Molestina, C, Roy, LD, Curry, JM, Mukherjee, P, Grdzelishvili, VZ. (2013) Oncolytic Vesicular Stomatitis Virus in an Immunocompetent Model of MUC1-Positive or MUC1-Null Pancreatic Ductal Adenocarcinoma. Journal of Virology 87, 10283-10294.

Williams, Tiffany C., M. Ayrapetyan and J.D. Oliver. (2014) Implications of chitin attachment on the environmental persistence and clinical nature of the human pathogen, Vibrio vulnificus.  Applied and Environmental Microbiology 2014 (published on line December, 2013  doi:10.1128/AEM.03811-13)

  • **Selected by the editors of Applied and Environmental Microbiology in the “Spotlight” section, which highlights research articles that are deemed of significant interes

 Rego, Stephen, Helms RS, Dréau D. (2014) Tumor necrosis factor-alpha-converting enzyme activities and tumor-associated macrophages in breast cancer. Immunology Research 58(1):87-100.

Rego, Stephen, Swamydas M, Kidiyoor A, Helms R, De Piante A, Lance AL, Mukherjee P, Dréau D. Soluble tumor necrosis factor receptors shed by breast tumor cells inhibit macrophage chemotaxis. Journal of Interferon and Cytokine Research 33(11):672-81.

Lawrence, M.M., Cooley, I.D., Arthur, S.T., Huett, Y.M., Howden, R. (2014) Factors influencing isometric exercise training induced reductions in resting blood pressure. Scand J Med Sci Sports

Oral Presentations

Coleman, Michelle and Dreau, D. Polymer Biomaterial Effects on MCF10A Breast Cells in 3D Culture Systems. Presented at Emerging Researchers National (ERN) Conference in STEM, 2014.

  • **2nd place in the oral presentation Biological Science category 

Williams, Tiffany. Illuminating the molecular underpinnings of the viable but nonculturable state in Vibrio vulnificus.  Presented at Vibrio2014 Conference, Scotland, 2014.

Poster Presentations

Wu, Shu-ta (Mike), Fowler, A., Ogle, C., Mukherjee, P.  Anti-cancer treatments delivered by antibody guided PLGA nanoparticles. Annual meeting of American Association of Cancer Research, California, 2014.

Wang, Lin, Lim, CK, Dang, H., Sayavedra-Soto, LA, Rodrigues, R., Konstantinidis, K., Klotz, M. Enrichment, sequencing and ongoing analysis of an ammonia-oxidizing bacterial community from sediments in Jiaozhou Bay, China. Southeastern Biogeochemistry Symposium, Georgia, 2014.

2013 Published Work

Matoo, Omera B., Ivanina, A.V., Ullstad, C., Beniash, E. and Sokolova, I.M. (2013). Interactive effects of elevated temperature and CO2 levels on metabolism and oxidative stress in two common marine bivalves (Crassostrea virginica and Mercenaria mercenaria). Comparative Biochemistry and Physiology A 164: 545–553.

Nath, Sritama, Daneshvar K, Roy LD, Grover P, Kidiyoor A, Mosley L, Sahraei M, Mukherjee P. (2013) MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes. Oncogenesis. Jun 17;2:e51

  • **Sritama’s thesis and this work in part led to an R03 award

Oral Presentations

Felt, Sebastien, Moerdyk-Schauwecker, M., and Grdzelishvili, VZ. Defects in Apoptotic Signaling in Pancreatic Ductal Adenocarcinoma Cells Resistant to Oncolytic Vesicular Stomatitis Virus. Presented at Annual Meeting of the American Society of Virology, Pennsylvania, 2013.

Hastie, Eric, Besmer, D, Shah, N, Murphy, A, Moerdyk-Schauwecker, M, Molestina, C, Das Roy, L, Curry, J, Mukherjee, P, Grdzelishvili, VZ. Oncolytic Vesicular Stomatitis Virus is an Immunocompetent Model of Pancreatic Cancer. Presented at Annual Meeting of the American Society of Virology, Pennsylvania, 2013.

Poster Presentations

Vestal, C. Greer, Bariar, BB, Richardson, C. Identification of dietary and environmental compounds that promote MLL-AF9 translocations. Presented at New York Academy of Sciences Bone Marrow Niche, Stem Cells, and Leukemia Conference, 2013.

Hastie, Eric, Besmer, D, Shah, N, Murphy, A, Moerdyk-Schauwecker, M, Molestina, C, Das Roy, L, Curry, J, Mukherjee, P, Grdzelishvili, VZ. Oncolytic Vesicular Stomatitis Virus in an Immunocompetent Model of Pancreatic Cancer. Presented at 7th International Meeting on Replicating Oncolytic Virus Therapeutics, Canada, 2013.

Khan, Bushra and Ringwood, Amy. Effects of hypoxia on metal bioavailability and tissue damage in estuarine bivalves. Presented at SETAC North America 34th Annual Meeting

**3rd place winner of the 2013 SETAC Foster Mayer PhD Best Student Poster Presentation

2012 Publications

Sendi H. Dual Role of miR-122 in Molecular Pathogenesis of Viral Hepatitis. Hepat Mon. 2012;12:312-4. PMID: 22783341)

Brandon-Warner E, Walling TL, Schrum LW, McKillop IH. 2012. Chronic ethanol feeding accelerates hepatocellular carcinoma progression in a sex-dependent manner in a mouse model of hepatocarcinogenesis. Alcohol Clin Exp Res. 36:641-653.

Dickinson G.H., Ivanina A.V., Matoo O.B., Pörtner H.O., Lannig G., Bock C., Beniash E., Sokolova I.M. 2012. Interactive effects of salinity and elevated CO2 levels on juvenile eastern oysters, Crassostrea virginica. Journal of Experimental Biology 215:29-43. DOI: 10.1242/jeb.061481.

Froelich, B.A, Williams, T.C., Noble, R.T., Oliver, J.D. 2012. Apparent Loss of Vibrio vulnificus from North Carolina Oysters Coincides with a Drought-Induced Increase in Salinity. Appl. Environ. Microbiol. June 2012 78:3885-3889; published ahead of print 23 March 2012, doi:10.1128/AEM.07855-11

Lakner AM, Steuerwald N, Walling T, Ghosh S, McKillop IH, Russo MW, Bonkovsky HB, Schrum LW. 2012. Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis. Hepatology. Jan 25. DOI:10.1002/hep.25613 [Epub ahead of print]. 

Morrison S.S., Williams T., Cain A., Froelich B., Taylor C., et al. (2012) Pyrosequencing-Based Comparative Genome Analysis of Vibrio vulnificus Environmental Isolates. PLoS ONE 7(5): e37553. doi:10.1371/journal.pone.0037553.

Murphy, Andrea M., Dahlia M. Besmer, Megan Moerdyk-Schauwecker, Natascha Moestl, David Ornelles, Pinku Mukherjee, and Valery Z. Grdzelishvili. 2012. Vesicular Stomatitis Virus as an oncolytic agent against pancreatic ductal adenocarcinoma, Journal of Virology, published online ahead of print on 11 January 2012. J. Virol. doi:10.1128/JVI.05640-11

Ryan Caballes F, Sendi H, Bonkovsky HL. 2012. Hepatitis C, porphyria cutanea tarda and liver iron: an update. Liver Int. Apr 17. doi:10.1111/j.1478-3231.2012.02794.x. PMID: 22510500.

Sendi H, Mehrab-Mohseni M. 2012. HFE Gene Mutations in Cryptogenic Cirrhosis Patients. Hepat Mon. 12:48-9. PMID:22451845

Sahraei, M, Das Roy L, Curry JM, Tinder TL, Nath S, Besmer D, Kidiyoor A, Ritu Dalia, Gendler SJ, and Mukherjee P. 2012. MUC1 Regulates PDGFA expression during pancreatic cancer progression: Oncogene: (Nature Publication) Jan 23. doi: 10.1038/onc.2011.651

Schettini, J, Kidiyoor A*, Besmer DM* Tinder TL, Das Roy L, Lustgarten J, Gendler SJ, Mukherjee P. 2012. Intratumoral Delivery of CpG-Conjugated Anti-MUC1 Antibody Enhances NK Cell Anti-Tumor Activity. Cancer Immunology Immunotherapy, PMID: 22543528 2012 Apr 28. [Epub ahead of print]
* Both authors contributed equally

Sokolova I.M., Frederich M., Bagwe R., Lannig G., Sukhotin A.A. (2012). Energy homeostasis as an integrative tool for assessing limits of environmental stress tolerance in aquatic invertebrates. Marine Environmental Research ttp://

Wang, M., Lu, P., Wu, B., Tucker, J.D., Cloer, C., and Lu, Q.  2012.  High efficiency and low toxicity of polyethyleneimine modified Pluronics (PEI-Pluronic) and gene delivery carriers in cell culture and dystrophic mdx mice.  J. Mater. Chem. 22:  6038-6046.

Wang M., Tucker J.D., Lu P., Wu B., Cloer C., Lu Q.  2012.  Tris[2-(acryloyloxy)ethyl]isocyanurate Cross-Linked Low-Molecular-Weight Polyethylenimine as Gene Delivery Carriers in Cell Culture and Dystrophic mdx Mice.Bioconjug Chem Apr 18;23(4):837-45  PMID: 22443086


Besmer, D.M., Curry, J.M., Roy, L.D., Tinder, T.L., Sahraei, M.M., Schettini, J.L., Hwang, S.-I., Lee, Y.Y., Gendler, S.J., and Mukherjee, P. 2011. Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis. Cancer Res. 71(13): 4432-42.

Brandon-Warner, E., Walling, T., Schrum, L.W. and McKillop, I.H. 2011. Chronic ethanol feeding accelerates hepatocellular carcinoma progression in a sex-dependent manner in a mouse model of hepatocarcinogesis. Alcoholism: Clinical and Experimental Research. PMID 22017344

Daneshvar K, Khan A, Goodliffe JM. 2011. Myc localizes to histone locus bodies during replication in Drosophila. PLoS One.;6(8):e23928. Epub 2011 Aug 23.

Dang H., Ruipeng Chen, Lin Wang, Sudong Shao, Lingqing Dai, Ying Ye, Lizhong Guo, Guiqiao Huang and Martin G. Klotz. 2011. Molecular characterization of putative biocorroding microbiota with a novel niche detection of Epsilon- and Zetaproteobacteria in Pacific Ocean coastal seawaters. Environmental Microbiology 13:3059-3074.

Day, S.A.*, Lakner, A.M.*, Moore, C.C., Yen, M.H., Clemens, M.G., Wu, E.S., and Schrum, L.W. 2011. Opioid-like compound exerts anti-fibrotic activity via decreased hepatic stellate cell activation and inflammation. Biochem. Pharmacol. 81:996-1003.
*These authors contributed equally

Ellefson, W.M., Lakner, A.M., Hamilton, A., McKillop, I.H., Bonkovsky, H.L., Steuerwald, N.M., Huet, Y.M., Schrum, L.W. 2011. Neonatal androgenization exacerbates alcohol-induced liver injury in adult rats, an effect abrogated by estrogen. PLoS ONE. Dec. 20.DOI:10.1371/journal.pone.0029463

Froelich, B.A. and J.D. Oliver. 2011. Orientation of mannitol related genes can further differentiate strains of Vibrio vulnificus possessing the vcgC allele. Adv. Stud. Biol. 3:151-160.

Furr,S.R., Chauhan, V.S., Moerdyk-Schauwecker, M., and Marriott, I. 2011. ­A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells. J.Neuroinflammation. 8: 99.

Giles, R.L., Galloway, E.R., Elliott, G.D., Parrow, M.W.  2011.  Two-stage fungal biopulping for improved enzymatic hydrolysis of wood.  Bioresource Technol. 102: 8011-8016.

Giles, R.L., Zackeru, J.C., Elliott, G.D., Parrow, M.W.  2011.  Fungal growth necessary but not sufficient for effective biopulping of wood for lignocellulosic ethanol applications.  Int. Biodeter. and Biodeg.67: 1-7.

Ivanina, A.V., B. Froelich, T. Williams, E.P. Sokolov, J.D. Oliver, and I.M. Sokolova. 2011. Interactive effects of cadmium and hypoxia on metabolic responses and bacterial loads of Eastern oysters Crassostrea virginica Gmelin. Chemosphere 82:377–389.

Lakner, A.M., Bonkovsky, H.L., Schrum, L.W. 2011. microRNAs: Fad or future of liver disease. World J. Gasteroenterol. 17: 2536-2542.

Lakner, A.M., Walling, T.L., McKillop, I.H., Schrum, L.W. 2011. Altered aquaporins expression and role in apoptosis during hepatic stellate cell activation. Liver Int. 31:42-51.

Mehrab-Mohseni M., Sendi H., Steuerwald N., Ghosh S., Schrum L.W., Bonkovsky H.L. 2011. Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV. World J. Gastroenterol. 17:1694-700.

Moore, C.C., Lakner, A.M., Yengo, C.M. and Schrum, L.W. 2011. Identification and function of nonmuscle myosin II isoforms in hepatic stellate cells. World J Hepatol. 3:184-197.

Mouzannar, R., McCafferty,, J., Benedetto, G., Richardson, C. 2011. Transcriptional and phospho-proteomic screens reveal stem cell activation of insulin-resistance and transformation pathways following a single minimally toxic episode of ROS, Int J Genomics Proteomics, 2(1): 2011.

Norris, EJ., Culberson CR., Narasimhan, S., Clemens, MG. The Liver as a Central Regulator of Hydrogen Sulfide.  Shock. 2011 Sep;36(3):242-50

Nguyen, N., Keller, S., Norris, E., Huynh, T., Clemens, MG., Shin, MC. Tracking Colliding Cells with in vivo Microscopy. IEEE Trans Biomed Eng. 2011 May 31. [Epub ahead of print]  

Powell, R., Hudson, L. C., Lambirth, K. C., Luth, D., Wang, K., Bost, K. L., and Piller, K. J. 2011. Recombinant expression of homodimeric 660 kDa human thyroglobulin in soybean seeds: an alternative source of human thyroglobulin, Plant Cell Rep 30, 1327-1338

Roy, L.D, Sahraei, M., Subramani, D.B., Besmer, D., Nath, S., Tinder, T.L., Bajaj, E., Shanmugam, K., Lee, Y.Y., Hwang, S.I.L, Gendler, S.J. and Mukherjee, P. 2011. MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene 30(12): 449-59.

Thompson, K.J., Lakner, A.M., Cross, B.W., Tsukada S, Rippe, R.A. McKillop, I.H. and Schrum, L.W. 2011. S-adenosyl-L-methionine inhibits collagen secretion in hepatic stellate cells via increased ubiquitination. Liver Int. DOI:10.1111/j.1478-3231.2011.02512.x

Thompson K.J., McKillop, I.H., Schrum, L.W. 2011. Targeting collagen expression in alcoholic liver disease. World J Gastroenterol. 17:2473-2481

Yip-Schneider, M.T., Doyle, C., McKillop, I.H., Wentz, S.C., Brandon-Warner, E., Matos, J.M., Sandrasegaran, K., Saxena, R., Hennig, M.E., Wu, H., Klein, P.J., Froehlich, J.C. and Schmidt, C.M. 2011. Alcohol preferring rats: a novel model of alcohol-induced liver neoplasia. Alcoholism: Clinical and Experimental Research. 35(12): 2216-2225


Somayaji, S.N., Huet, Y.M., Gruber, H.E. and Hudson, M.C. 2010. UV-killed Staphylococcus aureus enhances adhesion and differentiation of osteoblasts on bone-associated biomaterials. J Biomed Mater Res A. 95(2):574-9.

Brandon-Warner, E., Sugg, J.A., Schrum, L.W., and McKillop, I.H. 2010. Silibinin inhibits ethanol metabolism and ethanol-dependent cell proliferation in an in vitro model of hepatocellular carcinoma. Cancer Lett. 291:120—129.

Chauhan, V.S., Furr, S.R., Sterka, D.G. Jr., Nelson, D.A., Moerdyk-Schauwecker, M., Marriott, I., and Grdzelishvili, V.Z. 2010. Vesicular stomatitis virus infects resident cells of the central nervous system and induces replication-dependent inflammatory responses. Virology400: 187-196.

Dang H, Ruipeng Chen, Lin Wang, Lizhong Guo, Pingping Chen, Zuwang Tang, Fang Tian, Shaozheng Li and Martin G. Klotz. 2010. Environmental factors shape sediment anammox bacterial communities in hypernutrified Jiaozhou Bay, China. Applied and Environmental Microbiology 76:7036-7047.

Dang H, Jing Li, Ruipeng Chen, Lin Wang, Lizhong Guo, Zhinan Zhang, and Martin G. Klotz. 2010. Diversity, abundance, and spatial distribution of sediment ammonia-oxidizing Betaproteobacteria in response to environmental gradients and coastal eutrophication in Jiaozhou Bay, China. Applied and Environmental Microbiology 76:4691-4702

Furr, S.R., Moerdyk-Schauwecker, M., Grdzelishvili, V.Z., and Marriot, I. 2010. RIG-I mediates nonsegmented negative-sense RNA virus-induced inflammatory immune responses of primary human astrocytes. Glia. 2010 Jun 23. [Epub ahead of print] PubMed PMID: 20578054.

Inskeep, T. K., Stahl, C., Odle, J., Oakes, J., Hudson, L., Bost, K. L., and Piller, K. J. 2010. Oral vaccine formulations stimulate mucosal and systemic antibody responses against staphylococcal enterotoxin B in a piglet model, Clin Vaccine Immunol 17, 1163-1169.

Lakner, A.M., Moore, C.C., Gulledge, A.A., and Schrum, L.W. 2010. Daily genetic profiling indicates JAK/STAT signaling promotes early hepatic stellate cell transdifferentiation. World J Gastroenterol. 16:5047-5056.

Murphy A.M., Moerdyk-Schauwecker M., Mushegian A., Grdzelishvili V.Z. 2010 Sequence-function analysis of the Sendai virus L protein domain VI. Virology. 405(2):370-82.

Narang TK, Sendi H, Scobey M, Bonkovsky HL. 2010. Iron and hepatitis C.  Current Hepatitis Reports. 9:169-177

Rettew, J.A., Marriott, I., and Huet, Y.M. 2010. Sex differences in innate immune responses to bacterial pathogens. In: Sex Hormones and Immunity to Infection, Klien, S.L. and Roberts, C. (eds). Springer, New York, NY. Pp. 123-146.

Rettew, J.A., McCall, S.H., and Marriott, I. 2010. GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages. Mol. Cell. Endocrinol. 328: 87-92.

Shah NR, Sunderland A, Grdzelishvili VZ. 2010. Cell Type Mediated Resistance of Vesicular Stomatitis Virus and Sendai Virus to Ribavirin. PLoS ONE 5(6): e11265. doi:10.1371/journal.pone.0011265


Chauhan, V.S., Sterka, D.G., Jr., Furr, S.R., Young, A.B., and Marriott, I. 2009. NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens. Glia. 57:141-423.

Froelich, B., A. Ringwood, I. Sokolova, and J.D. Oliver. 2009. Uptake and depuration of the C- and E-genotype of Vibrio vulnificus by the Eastern oyster (Crassostrea virginica). Environ. Microbiol. Rep. Environ. Microbiol. Rep. 2:112-115.

Khan A., W. Shover, and J. M. Goodliffe. 2009. Su(z)2 Antagonizes Auto-Repression of Myc in Drosophila, Increasing Myc Levels and Subsequent Trans-Activation. PLoS ONE doi:10.1371/journal.pone.0005076.

Miller AM and Zhang JX. 2009. Altered Endothelin-1 Signaling in Production of Thromboxane A2 in Kupffer Cells from Bile Duct Ligated Rats. Cellular & Molecular Immunology 6 (6): 441-452.

Murphy A.M., Grdzelishvili VZ. 2009. Identification of sendai virus L protein amino acid residues affecting viral mRNA cap methylation. Journal of Virology 83(4):1669-1681. PMID: 19052078

Rettew, J.A., Huet, Y.M., and Marriott, I. (2009). Estrogens augment cell surface TLR4 expression on murine macrophages and regulates sepsis susceptibility in vivo. Endocrinology.150:3877-3884

Salles, F.T., Merritt, R.C., Manor, U., Dougherty, G.W., Sousa, A.D.,Moore, J.E., Yengo, C.M., Dosé, A.C., and Kachar, B. 2009. Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments. Nature Cell Biology2009 Apr;11(4):443-50. Epub 2009 Mar 15.

Sendi H, Mehrab-Mohseni M, Shahraz S, Norder H, Alavian SM, Noorinayer B, Zali MR, Pumpens P, Bonkovsky HL, Magnius LO. 2009. CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA. J Clin Virol. 46:259-64. PMID: 19748824


Chauhan, V.S., Sterka, D.G. Jr., Gray, D.L., Bost, K.L., and Marriott, I. (2008). Neurogenic exacerbation of microglial and astrocyte responses to Neisseria meningitidis and Borrelia burgdorferi. J. Immunol. 180: 8241-8249.

Dosé, A.C., Ananthanarayanan, S., Moore, J.E., Burnside, B., and Yengo, C.M. (2008). The kinase domain alters the kinetic properties of the myosin IIIA motor. Biochemistry 47: 2485-2496.

Furr, S.R., Chauhan, V.S.,Sterka, D.G. Jr., Grdzelishvili, V., and Marriott, I. Characterization of retinoic acid-inducible gene-I expression in primary murine glia following exposure to vesicular stomatitis virus. J. Neurovirol. 7: 1-11.

Jones, M.K., E. Warner, and J.D. Oliver. 2008. Survival and in situgene expression of Vibrio vulnificus at varying salinities in estuarine environments. Appl. Environ. Microbiol. 74:182-187.

Karaa A, Thompson KJ, McKillop IH, Clemens MG, Schrum, LW. (2008) S-adenosyl-L-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model. Shock. 30:197-205.

Keller, J.M., Huet-Hudson, Y. and L.J. Leamy. 2008. Effects of 2,3,7,8 tetrachlorodibenzo-p-dioxin on molar development among non-resistant inbred strains of mice: A geometric morphometric analysis. Growth, Development & Aging 71: 13-27.

Keller, J.M., M.L. Zelditch, Y M. Huet, and L.J. Leamy. 2008. Genetic differences in sensitivity to alterations of mandible structure caused by the teratogen 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicologic Pathology 36: 1006-1013.

McCall, S.H, Sahraei, M., Young, A.B., Worley, C.S., Duncan, J.A., Ting, J.P. and Marriott, I. (2008). Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. J. Bone. Min. Res. 23: 30-40.

Pillai, R.R. Somayaji, S.N, Rabinovich, M., Hudson, M.C. and Gonsalves, K.E. (2008) Nafcillin. Loaded PLGA. Nanoparticles for Treatment of Osteomyelitis. Biomed. Mater. 3: 34114 [Epub ahead of print]

Rabinovich, M. M., Somayaji, S.N., Pillai, R.R., Hudson, M.C., Ellington, K., Bosse, M., Horton, J., and Gonsalves, K.E. (2008) Active Polymer Nanoparticles: Delivery of Antibiotics. Proc. Materials Res. Soc. (in press).

Rettew, J.A., Huet-Hudson, Y.M., and Marriott, I. (2008). Testosterone reduces macrophage expression of Toll-like receptor 4, a trigger for inflammation and innate immunity. Biol. Reprod. 78:432-437.

Somayaji, S. N., S. Ritchie, M. Sahraei, I. Marriott, and M. C. Hudson. 2008. Staphylococcus aureus induces RANK-L and Prostaglandin E2 Expression in Infected Murine Osteoblasts. Infect. Immun. 76: 5120-5126.

Warner, E.B. and J.D. Oliver. 2008. Population structure of two genotypes of Vibrio vulnificus in oysters (Crassostrea virginica) and sea water. Appl. Environ. Microbiol. 74:80-85.


Dosé, A.C., Ananthanarayanan, S., Moore, J.E., Burnside, M.B. and Yengo, C.M. (2007). Kinetic mechanism of human myosin IIIA. J. Biol. Chem. 282:216-231.

Garg, R., Tolbert, M., Oakes, J.L., Clemente, T.E., Bost, K.L., and Piller, K.J. (2007) Chloroplast targeting of FanC, the major antigenic subunit of Escherichia coli K99 fimbriae, in transgenic soybean. Plant Cell Rep. 26:1011-1023.

Hicks-Little CA, Thatcher JR, Hauth JM, Goldfuss AJ, Cordova ML. (2007) Menstrual cycle stage and oral contraceptive effects on anterior tibial displacement in collegiate female athletes. J. Sports Med. Phys. Fitness. 47:255-260.

Jablonski, EM, Mattocks, AM, Sokolov, E, Koniaris, LG, Hughes, FM, Fausto, N, Pierce, RH & McKillop, IH (2007). Decreased aquaporin expression leads to increased resistance to apoptosis in hepatocellular carcinoma. Cancer Letters 250(1):36-46

Keller J.M., Huang J.C., Huet-Hudson Y., and L.J. Leamy. (2007) The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on molar and mandible traits in congenic mice: A test of the role of the Ahrlocus. Toxicology242: 52-62.

Keller, J.M., Huet-Hudson, Y.M. and Leamy, L.J. (2007). Qualitative effects of dioxin on molars vary among inbred mouse strains. Arch. Oral Biol. 52:450-454.

Lightfoot, JT, MJ Turner, AM Kleinfehn, AE Jedlicka, T Oshimura, J Marzec, W Gladwell, LJ Leamy, SR Kleeberger. (2007) Quantitative trait loci (QTL) associated with maximal exercise endurance in mice. J. Appl. Physiology 103:105-110.

Marriott, I., Miller, J.R., and Sahraei, M. (2007) Therapeutic strategies against the inflammation and bone loss associated with osteomyelitis. Curr. Opin. Investig. Drugs.8: 887-899.

Miller AM, Masrorpour M, Klaus C, and Zhang JX. (2007). LPS Exacerbates Endothelin-1 Induced Activation of Cytosolic Phosoholipase A2 and Thromboxane A2 Production from Kupffer Cells of the Prefibrotic Rat Liver. J Hepatology.46(2):276-8.

Olson, CM, Hedrick, MN, Izadi, H, Bates, TC, Olivera, ER, Anguita, J. (2007). p38 Mitogen-Activated Protein Kinase Controls NF- Kappa B Transcriptional Activation and Tumor Necrosis Factor Alpha Production through RelA Phosphorylation Mediated by Mitogen- and Stress-Activated Protein Kinase 1 in Response to Borrelia burgdorferi Antigens. Infect. Immun. 75(1):270-277.

Sefton JM, Hicks-Little CA, Koceja DM, Cordova ML. (2007) Modulation of soleus H-reflex by presynaptic spinal mechanisms during varying surface and ankle brace conditions. Clin. Neurophys. 37:15-21.

Warner, E. and J.D. Oliver. (2007) Refined medium for direct isolation of Vibrio vulnificus from oyster tissue and sea water. Appl. Environ. Microbiol. 73:3098-3100..

Xu H, Lee CY, Clemens MG, and Zhang JX. (2007). Inhibition of TXA2 Synthesis with OKY-046 Improved Liver Preservation by Prolonged Hypothermic Machine Perfusion in Rats. J Gastroenterol Hepatol.


Gasper-Smith, N., Marriott, I., and Bost, K.L. (2006). Murine gammaherpesvirus 68 limits naturally occurring CD4+CD25+ T regulatory cell activity following infection. J. Immunol. 177:4670-4678.

Gasper-Smith, N., Singh, S., and Bost, K.L. (2006). Limited IL-6 production following infection with murine gammaherpesvirus 68. Arch. Virol.151:1423-1430.

Hedrick, MN, Olson, CM, Conze, DB, Bates, TC, Rincón, M, Anguita, J (2006). Control of Borrelia burgdorferi-specific CD4+-T-cell effector function by interleukin-12- and T-cell receptor-induced p38 mitogen-activated protein kinase activity. Infect Immun. 74(10):5713-5717

Jablonski EM, Hughes FM Jr (2006) The Potential Role of Caveolin-1 in inhibition of aquaporins during the AVD. Biol Cell98:33-42

Karaa A, Kamoun WS, Xu H, Zhang J, Clemens MG. (2006). Differential effects of oxidative stress on hepatic endothelial and Kupffer cell eicosanoid release in response to endothelin-1. Microcirculation. 13:457-66.

Kamoun WS, Karaa A, Kresge N, M. Merkel S, Korneszczuk K, Clemens MG. (2006). LPS Inhibits Endothelin-1 Induced Endothelial Nitric Oxide Synthase Activation through a Negative Feedback Involving Caveolin-1. Hepatology 43:182-90

Moran, DM, Jablonski, EM, Koniaris, LG, Cahill, PA, Halberstadt, CR and McKillop, IH. (2006). Microencapsulation of engineered cells to deliver sustained high circulating levels of interleukin-6 to study hepatocellular carcinoma progression. Cell Transplantation, 05-06

Moran, D, Mattocks, AM, Koniaris, LG, Cahill, PA, & McKillop, IH (2006). Interleukin-6 (IL-6) mediates G0/G1 growth arrest in hepatocellular carcinoma through a STAT3 dependent mechanism. Liv Int, 07/06.

Rasley, A., Tranguch, S.L., Rati, D.M., and Marriott, I. (2006). Murine microglia express the immunosuppressive cytokine, interleukin-10, following exposure to Borrelia burgdorferi orNeisseria meningitidis. Glia.53: 583-592

Sefton JM, Hicks-Little CA, Koceja DM, Cordova ML. (2006) Effect of inversion and ankle bracing on peroneus longus Hoffmann reflex. Scand. J. Med. Sci. Sports (epub ahead of print).

Sterka, D. Jr., Rati, D.M., and Marriott, I. (2006). Functional expression of NOD2, a novel pattern recognition receptor for bacterial motifs, in primary murine astrocytes. Glia. 53:322-330.

Sterka, D. Jr. and Marriott, I. (2006). Characterization of nucleotide-binding oligomerization domain (NOD) protein expression in primary murine microglia. J Neuroimmunol. 179:65-7

Sun, M., Oakes, J.L., Ananthanarayanan, S.K., Hawley, K.H., Tsien, R.Y., Adams, S.R., and Yengo, C.M. (2006). Dynamics of the upper 50 kDa domain of myosin V examined with fluorescence resonance energy transfer. J Biol Chem.281:5711-5717.

Yokoyama Y, Wawrzyniak A, Sarmadi AM, Baveja R, Gruber HE, Clemens MG, Zhang JX. (2006). Hepatic arterial flow becomes the primary supply of sinusoids following partial portal vein ligation in rats. J Gastroenterol Hepatol. 21:1567-74.


Motameni, ART; Bates, TC; Juncadella, IJ; Petty, C; Hedrick, MN;Anguita, J (2005). Distinct bacterial dissemination and disease outcome in mice subcutaneously infected with Borrelia burgdorferiin the midline of the back and the footpad. FEMS Immunol. Med. Microbiol. 45(2):279-284.

Xu H, Korneszczuk K, Karaa A, Lin T, Clemens MG, Zhang JX. (2005). Thromboxane A2 from Kupffer cells contributes to the hyperresponsiveness of hepatic portal circulation to endothelin-1 in endotoxemic rats. Am J Physiol Gastrointest Liver Physiol. 288(2):G277-83.

Xu H, Zhang JX, Jones JW, Southard JH, Clemens MG, Lee CY. (2005). Hypothermic machine perfusion of rat livers preserves endothelial cell function. Transplant Proc. 37(1):335-7.


Ashburn JH, Baveja R, Kresge N, Korneszczuk K, Keller S, Karaa A,Yokoyama Y, Zhang JX, Huynh T, Clemens MG. (2004). Remote trauma sensitizes hepatic microcirculation to endothelin via caveolin inhibition of eNOS activity. Shock 22(2):120-30.

Elsawa SF, Bost KL. (2004). Murine gamma-herpesvirus-68-induced IL-12 contributes to the control of latent viral burden, but also contributes to viral-mediated leukocytosis. J Immunol. 172(1):516-24.

Gasper-Smith, N. and Bost, K.L. (2004). Initiation of the host response against murine gammaherpesvirus infection in immunocompetent mice. Viral Immunol. 17: 473-480.

Jablonski EM, Webb AN, McConnell NA, Riley MC, Hughes FM Jr. (2004). Plasma membrane aquaporin activity can affect the rate of apoptosis but is inhibited after apoptotic volume decrease. Am J Physiol Cell Physiol. 286(4):C975-85. Epub.

Jain S, Xu H, Duncan H, Jones JW Jr, Zhang JX, Clemens MG, Lee CY. (2004). Ex-vivo study of flow dynamics and endothelial cell structure during extended hypothermic machine perfusion preservation of livers. Cryobiology. 48(3):322-32.

Lin, T., and Bost, K.L. (2004). STAT3 activation in macrophages following in vivo or in vitro infection with Salmonella. Biochem. Biophys. Res. Comm. 321:828-834.

Motameni, A-RT; Juncadella, IJ; Ananthanarayanan, SK; Hedrick, MN; Huet-Hudson, Y; Anguita, J (2004). Delivery of the Immunosuppressive Antigen Salp15 to Antigen-Presenting Cells by Salmonella enterica Serovar Typhimurium aroA Mutants. Infect. Immun.72(6):3638-3642.

Paxian M, Keller SA, Baveja R, Korneszczuk K, Huynh TT, Clemens MG. (2004). Functional link between ETB receptors and eNOS maintain tissue oxygenation in the normal liver. Microcirculation. 11(5):435-49.

Rasley A, Bost KL, Marriott I. (2004). Murine gammaherpesvirus-68 elicits robust levels of interleukin-12 p40, but not interleukin-12 p70 production, by murine microglia and astrocytes. J Neurovirol. 10(3):171-80.

Rasley A, Marriott I, Halberstadt CR, Bost KL, Anguita J. (2004). Substance P augments Borrelia burgdorferi-induced prostaglandin E2 production by murine microglia. J Immunol. 172(9):5707-13.

Sefton JM. (2004). Myofascial release for athletic trainers, Part 1: Theory and session guidelines. Athletic Therapy Today. ;9(1):148-149.

Sefton JM. (2004). Myofascial release for athletic trainers, Part 2: Guidelines and techniques. Athletic Therapy Today. 9(2): 52-53.

Sefton JM. (2004). Myofascial release for athletic trainers, Part 3:Specific techniques for the athletic trainer. Athletic Therapy Today. 9(3):52-53.

Xu, H, Lee CY, Clemens MG, Zhang JX. (2004). Prolonged hypothermic machine perfusion preserves hepatocellular function but potentiates endothelial cell dysfunction in rat livers. Transplantation. 77(11):1676-82


Alexander EH,Rivera FA, Marriott I, Anguita J, Bost KL, Hudson MC. (2003). Staphylococcus aureus - induced tumor necrosis factor - related apoptosis - inducing ligand expression mediates apoptosis and caspase-8 activation in infected osteoblasts. BMC Microbiol.2;3(1):5.

Anguita, J, Hedrick, MN, Fikrig, E. (2003). Adaptation of Borrelia burgdorferi in the tick and the mammalian host. FEMS Microbiol Rev. 27(4):493-504

Bowman CC, Rasley A, Tranguch SL, Marriott I. (2003). Cultured astrocytes express toll-like receptors for bacterial products. Glia. 43(3):281-91.

Elsawa SF,Taylor W, Petty CC, Marriott I, Weinstock JV, Bost KL. (2003). Reduced CTL response and increased viral burden in substance P receptor-deficient mice infected with murine gamma-herpesvirus 68. J Immunol. 170(5):2605-12.

He, W., K. E. Gonsalves, N. Batina, D. B. Poker, E. Alexander, and M. Hudson. (2003). Micro/Nanomachining of of Polymer Surface for Promoting Osteoblast Cell Adhesion. Biomed. Microdevices 5:101-108.

Jablonski EM,NcConnell NA, Hughes FM Jr, Huet-Hudson YM. (2003). Estrogen regulation of aquaporins in the mouse uterus: potential roles in uterine water movement. Biol Reprod. 9(5):1481-7. Epub .

Peacock JW, Elsawa SF, Petty CC, Hickey WF, Bost KL. (2003).Exacerbation of experimental autoimmune encephalomyelitis in rodents infected with murine gammaherpesvirus-68. Eur J Immunol. 3(7):1849-58.

Taylor WR, Rasley A,Bost KL, Marriott I. (2003). Murine gammaherpesvirus-68 infects microglia and induces high levels of pro-inflammatory cytokine production. J Neuroimmunol. 136(1-2):75-83.

Yokoyama Y, Xu H, Kresge N, Keller S, Sarmadi AH, Baveja R,Clemens MG, Zhang JX. (2003). Role of thromboxane A2 in early BDL-induced portal hypertension. Am J Physiol Gastrointest Liver Physiol. 284(3):G453-60. Epub.


Anguita, J; Barthold, SW; Persinski, R; Hedrick, MN; Huy, CA;Davis, RJ; Flavell, RA; Fikrig, E. (2002). Murine Lyme Arthritis Development Mediated by p38 Mitogen-Activated Protein Kinase Activity.
J. Immunol. 168(12):6352-6357.

Baveja R, Kresge N, Ashburn JH, Keller S, Yokoyama Y, Sonin N, Zhang JX, Huynh T, Clemens MG. (2002). Potentiated hepatic microcirculatory response to endothelin-1 during polymicrobial sepsis. Shock. 18:415-22.

Baveja R, Keller S, Yokoyama Y, Sonin N, Clemens MG, Zhang JX. (2002) LPS-induced imbalanced expression of hepatic vascular stress genes in cirrhosis: possible mechanism of increased susceptibility to endotoxemia. Shock.17(4):316-21

Baveja R, Yokoyama Y, Korneszczuk K, Zhang JX, Clemens MG. (2002) Endothelin 1 impairs oxygen delivery in livers from LPS-primed animals. Shock.17(5):383-8.

Gasper, N. A., Petty, C. C., Schrum, L. W., Marriott, I., and Bost, K. L. 2002. Bacterium-induced CXCL10 secretion by osteoblasts can be mediated in part through toll-like receptor 4, Infect Immun 70, 4075-4082.

McConnell NA,Yunus RS, Gross SA, Bost KL, Clemens MG, Hughes FM Jr. (2002). Water permeability of an ovarian antral follicle is predominantly transcellular and mediated by aquaporins. Endocrinology. 143(8):2905-12.

Rasley A, Anguita J, Marriott I. (2002). Borrelia burgdorferi induces inflammatory mediator production by murine microglia. J Neuroimmunol. 130:22-31.

Rasley A, Bost KL, Olson JK, Miller SD, Marriott I. (2002) Expression of functional NK-1 receptors in murine microglia. Glia. 2002 Mar 1;37(3):258-67.

Rensing H, Bauer I, Zhang JX, Paxian M, Pannen BH, Yokoyama Y, Clemens MG, Bauer M. (2002). Endothelin-1 and heme oxygenase-1 as modulators of sinusoidal tone in the stress-exposed rat liver. Hepatology. 36(6):1453-65.

Yokoyama Y, Alterman DM, Sarmadi AH,Baveja R, Zhang JX, Huynh T, Clemens MG. (2002). Hepatic vascular response to elevated intraperitoneal pressure in the rat. J Surg Res.15;105(2):86-94.

Yokoyama Y, Baveja R, Kresge N, Sonin N, Nakanishi K, Zhang JX, Gitzelmann CA, Clemens MG. (2002). Endothelin receptor remodeling induces the portal venous hyper-response to endothelin-1 following endotoxin pretreatment. Shock. 17(1):36-40.


Alexander EH, Hudson MC. (2001). Factors influencing the internalization of Staphylococcus aureus and impacts on the course of infections in humans. Appl Microbiol Biotechnol. 56(3-4):361-6. Review.

Alexander EH, Bento JL, Hughes FM Jr, Marriott I, Hudson MC, Bost KL. (2001). Staphylococcus aureus and Salmonella enterica serovar Dublin induce tumor necrosis factor-related apoptosis-inducing ligand expression by normal mouse and human osteoblasts. Infect Immun. 69(3):1581-6.

Baveja R, Zhang JX, Clemens MG. (2001). In vivo assessment of endothelin-induced heterogeneity of hepatic tissue perfusion. Shock. 15(3):186-92.

Ellington JK, Elhofy A, Bost KL, Hudson MC. (2001). Involvement of mitogen-activated protein kinase pathways in Staphylococcus aureus invasion of normal osteoblasts. Infect Immun. 2001 Sep;69(9):5235-42.

Peacock JW, Bost KL. (2001). Murine gammaherpesvirus-68-induced interleukin-10 increases viral burden, but limits virus-induced splenomegaly and leukocytosis. Immunology. 2001 Sep;104(1):109-17.

Yokoyama Y, Wawrzyniak A, Baveja R, Sonin N, Clemens MG, Zhang JX. (2001). Altered endothelin receptor expression in prehepatic portal hypertension predisposes the liver to microcirculatory dysfunction in rats. J Hepatol. 35(1):29-36.

Yokoyama Y, Baveja R, Sonin N, Clemens MG, Zhang JX. (2001). Hepatic neovascularization after partial portal vein ligation: novel mechanism of chronic regulation of blood flow. Am J Physiol Gastrointest Liver Physiol. 280(1):G21-31.


Bauer M, Bauer I, Sonin NV, Kresge N, Baveja R, Yokoyama Y, Harding D, Zhang JX, Clemens MG. (2000). Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver. Hepatology. 31(4):937-47.

Elhofy A, Marriott I, Bost KL. (2000). Salmonella infection does not increase expression and activity of the high affinity IL-12 receptor. J Immunol. 165(6):3324-32.

Marriott I, Mason MJ, Elhofy A, Bost KL. (2000). Substance P activates NF-kappaB independent of elevations in intracellular calcium in murine macrophages and dendritic cells. J Neuroimmunol. 102(2):163-71..

Peacock JW, Bost KL. (2000). Infection of intestinal epithelial cells and development of systemic disease following gastric instillation of murine gammaherpesvirus-68. J Gen Virol. 81(Pt 2):421-9.

Yokoyama Y, Baveja R, Sonin N, Nakanishi K, Zhang JX, Clemens MG. (2000). Altered endothelin receptor subtype expression in hepatic injury after ischemia/reperfusion. Shock. 13(1):72-8.


Elhofy A, Bost KL. (1999). Limited interleukin-18 response in Salmonella-infected murine macrophages and in Salmonella-infected mice. Infect Immun. 67(10):5021-6.


Elhofy A, Bost KL. (1998). Limitations for purification of murine interleukin-18 when expressed as a fusion protein containing the FLAG peptide. Biotechniques. 25(3):426-33.

Publications by Ph.D. exchange students doing research with Biology Program faculty members at UNC Charlotte.

Cherkasov A.S., Grewal S., Sokolova I.M. (2007). Combined effects of temperature and cadmium exposure on haemocyte apoptosis and cadmium accumulation in the eastern oysterCrassostrea virginica (Gmelin). J Thermal Biol 32(3):162 - 170.

Cherkasov A.S., Overton, R.A. Jr, Sokolov E.P., Sokolova I.M. (2007). Temperature-dependent effects of cadmium and purine nucleotides on mitochondrial aconitase from a marine ectotherm,Crassostrea virginica: a role of temperature in oxidative stress and allosteric enzyme regulation. J Experimental Biol 210:46-55.

Cherkasov A.S., Ringwood A.H., Sokolova I.M. (2006). Effects of cadmium exposure on mitochondrial function are modulated by acclimation temperature in eastern oysters Crassostrea virginicaGmelin (Bivalvia: Ostreidae). Environ Toxicology & Chem. 25: 2461-2469.

Lannig G., Cherkasov A.S., Sokolova I.M. (2006). Temperature-dependent effects of cadmium on mitochondrial and whole-organism bioenergetics of oysters (Crassostrea virginica). Marine Environmental Research 62: S79-S82.

Cherkasov A.S., Biswas P.K., Ridings D.M., Ringwood A.H., Sokolova I.M. (2006). Effects of acclimation temperature and cadmium exposure on cellular energy budgets in a marine molluskCrassostrea virginica: Linking cellular and mitochondrial responses. J Experimental Biol. 209:1274-1284.