Research

The Department of Biological Sciences of UNC Charlotte is committed to excellence in fundamental and applied biological research and prides itself on the breadth of its research including molecular and cell biology; immunology; genetics; microbiology; animal, plant and microbial physiology; developmental biology; behavior; ecology and evolution.  Research of the Department of Biological Sciences also involves a strong applied component using fundamental biological studies to address key environmental and health-related issues, disease, ecological sustainability, and global change. Doctoral, Master’s and undergraduate students are all encouraged to pursue research and develop new approaches to fundamental biological questions. The Department has one of the best Honors undergraduate student research programs on campus and it is strongly committed to research outreach by providing research opportunities for high school students.


Now available: Graduate student Travel Award to attend a meeting and present your work $500. There are two awards each year. Deadlines for consideration are February 1st and June 1st each year. Click on the link below to apply.

Graduate Student Travel Award


Our students at all levels-- Doctoral, Master's, Undergraduate, and High School -- have the opportunity to publish their work, and present at national and international meetings. 

MOST RECENT PUBLICATIONS:

Wallace BD, Berman Z, Mueller GA, Lin Y, Chang T, Andres SN, Wojtaszek JL, DeRose EF, Appel CD, London RE, Yan S, Williams RS.  APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 114 (2): 304-309. 2017.

Burcal CJ, Wikstrom EA. Examining the Relationship Between Chronic Ankle Instability Symptoms and Dual-Task Balance Performance. International Journal of Athletic Therapy and Training. In press, 2017

Burcal CJ, Hoch MC, Wikstrom EA. Effects of a Stocking on Plantar Sensation in Individuals with and without Ankle Instability. Muscle & Nerve. In press, 2017.

Burcal CJ, Trier AY, Wikstrom EA. Balance Training vs. Balance Training with STARS in CAI Patients: A Randomized Controlled Trial. Journal of Sport Rehabilitation. 24:1-30, 2016

Song K, Burcal CJ, Hertel J, Wikstrom EA. Increased Visual Utilization in Chronic Ankle Instability: A Meta-analysis. Medicine and Science in Sports and Exercise. 48(10):2046-2056, 2016.

Burcal CJ, Wikstrom EA. Cognitive Loading-Induced Sway Alterations are Similar in Those with Chronic Ankle Instability and Uninjured Controls. Gait Posture. 48:95-98, 2016

A. Martinez, A. Burmeister, G. Ramesh, L. Doyle-Meyers, I. Marriott, and M. Philipp. Aprepitant limits in vivi neuroinflammatory responses in a rhesus model of Lyme neuroborreliosis. Journal of Neuroinflammation, 2017

TJ Carrier and AM Reitzel. The hologenome across environments and the implications of a host-associated microbial repertoire. Frontiers in Microbiology, in press.

Williams, EA & TJ Carrier. Chapter 19: An -omics perspective on marine invertebrate larvae. In: TJ Carrier, AM Reitzel, & A Heyland (eds.) Evolutionary Ecology of Marine Invertebrate Larvae. Oxford University Press, 2017.

Hastie E.*, Cataldi M.*, Moerdyk-Schauwecker M.J.*Felt S.A.*, Steuerwald N., Grdzelishvili V.Z. Novel Biomarkers of Resistance of Pancreatic Cancer Cells  to Oncolytic Vesicular Stomatitis Virus. Oncotarget, 2016 (*equal contribution)

L. Moore, L Da Roy, R, R. Zhou, P. Grover, S. Wu, J. Curry, L. Dillon, P. Puri, M. Yazdanifar, R. Puri, P, Mukherjee, D. Dreau. Antibody guided in vivo imaging for early detection of mammary gland tumors. Translational oncology 9(4) May 2016.

Zhang, H., Li, C., Davis, E. L., Wang, J., Griffin, J. D., Kofsky, J., and Song, B.-H. Genome-Wide Association Study of Resistance to Soybean Cyst Nematode (Heterodera glycines) HG Type 2.5.7 in Wild Soybean (Glycine soja). Frontiers in Plant Science, 7, 1214, 2016.

H. Zhang, N. Mittal, L.J. Leamy, O. Barazani, B. Song. Back into the wild- Apply untapped genetic diversity of wild relatives for crop improvement. Evolutionary Applications (Wiley Publications, Open Access Journal), January 2017

Phippen, B. L., and J. D. Oliver. Impact of hypoxia on gene expression patterns by the human pathogen, Vibrio vulnificus, and bacterial community composition in a North Carolina estuary, GeoHealth, 2017.

B. FroelichB. Phippen, P. Fowler, R. Noble, and J.D. Oliver. Differences in total Vibrio spp., V. vulnificus, and V. parahaemolyticus abundance between clams and oysters in North Carolina. Appl. Environ. Microbiol. 83:2-11, 2017. 

M Yazdanifar, R Zhou and P Mukherjee. Emerging immunotherapeutics in adenocarcinomas: A focus on CAR-T cells, Current Trends in Immunology, Vol. 17, 95 – 115, 2016.


MOST RECENT POSTER PRESENTATIONS:

N. Attal, MG Clemens. Sonic hedgehog in apoptotic T cell derived microparticles modulate endothelial cytoskeleton in inflammation via rho kinase pathway. Presented at SHOCK Society Meeting Austin Texas, June 2016.

Burcal CJ, McKeon PO, Wikstrom EA. Two-Weeks of Ankle Joint Mobilization does not Improve Gait Initiation Outcomes in Patients with Chronic Ankle Instability. Presented at American Society of Biomechanics Annual Meeting, Raleigh, NC. July 2016

A. Burmeister, M. Johnson, G. Ramesh, A. Martinez, M. Philipp and I. Marriott. Constitutive and inducible expression of the neurokinin-1 receptor for the inflammatory neuropeptide substance P in human microglia and astrocytes. Presented at the American Association of Immunologists conference Seattle, WA May 2016.

Felt S.A., Grdzelishvili V.Z. Role of early steps of infection in the resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus. Presented at European Congress of Virology, Hamburg, Germany. Oct. 2016.

P. Grover, M.D. Nye, M. Yazdanifar, M. Ahmad, R. Zhou, L. Das Roy, K. Grover, and P. Mukherjee. MUC1 regulates TGF-β function in Pancreatic Cancer. Presented at the American Association for Cancer Research Annual Meeting, Washington D.C., April 2017.

J Kofsky, B Song. Dissecting the genetic basis of early vigor traits of the soybean wild relative, Glycine soja, Presented at the Plant Molecular Biology Consortium. Wilmington, NC., September, 2016.

J Kofsky, B Song. Genome Wide Association Study of Early Vigor Traits in Wild Soybean (Glycine soja). Presented at Southeastern Population Ecology and Evolutionary Genetics conference. Madison, FL., October, 2016.

JR Huot, MM Lawrence, B Peck, J Marino, ST Arthur. A myogenic switch: Notch and mTOR. Presented at the SEACSM Annual Meeting, Where?, February 2017.

WB Leach, R Peres, AM Reitzel. Diel lighting impacts on behavior and opsin expression in a coastal cnidarian. Presented at Society for Integrative and Comparative Biology Conference, New Orleans, LA 2017.

N Mittal, H Zhang and B Song. Glyceollin Pathway Regulation in Response to Soybean Cyst Nematodes. Presented at the 43rd Annual Southeastern Population Ecology and Evolutionary Genetics Madison, FL. October 2016.

S. Pennnington, MG Clemens. Effects of H2S and Endothelin on Reactive Oxygen and Mitochondrial Membrane Potential in Endotoxemia. Presented at SHOCK Society Meeting Austin Texas, June 2016.

B Phippen and J.D. Oliver. In Situ Genetic Responses by Distinct Genotypes of Vibrio vulnificus Experiencing Oxygen Limitation in Oysters and Water, and Parallel Bacterial Community Analyses. Presented at Southeastern Biogeochemistry Symposium, Athens, GA April 2017.

M Yazdanifar, R Zhou, S Wu, P Grover and P Mukherjee. A novel anti-MUC1 CAR T cell drives immunity to pancreatic cancer. Presented at the American Association for Cancer Research Annual Meeting, Washington D.C., April 2017.

R. Zhou, L Das Roy, M Yazdanifar, L Moore, E Cherian, C Livasy, P Mukherjee. Development of combinatorial immune therapy using tMUC1-specific chimeric antigen receptor-redirected T cells for the treatment of triple negative breast cancer. Presented at American Association of Cancer Reseach Annual Meeting, Boston MA, April 2016.


MOST RECENT ORAL PRESENTATIONS:

Burcal CJ, Sandrey MA, McKeon PO, Wikstrom EA. Predicting Dynamic Balance Improvements Following 4-Weeks of Balance Training in Chronic Ankle Instability Patients. Presented at the Human Movement Science Curriculum and Biomechanics Symposium, Chapel Hill, NC. March 2017

Burcal CJ, McKeon PO, Wikstrom EA. A Clinical Prediction Rule for Patients with Chronic Ankle Instability who Respond to Plantar Massage Treatments. Presented at the National Athletic Trainers’ Association Annual Meeting, Baltimore, MD. June 2016

A. Burmeister, M. Johnson, G. Ramesh, A. Martinez, M. Philipp and I. Marriott. Constitutive and inducible expression of the neurokinin-1 receptor for the inflammatory neuropeptide substance P in human microglia and astrocytes. Presented at the American Association of Immunologists conference Seattle, WA, May 2016.

Felt S.A., Grdzelishvili V.Z. Role of Virus Attachment in the Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus. Presented at American Society of Virology,  Blacksburg, VA, June 2016.

TR Gaspar, R Chi, AH Ringwood. Plastic pollution: Particle uptake and the Trojan horse effect. Presented at Carolinas Society of EnvironmentalToxicology & Chemistry meeting Raleigh NC May 2016.

N. Mittal, A. Trautman, B. Kiefer, B. Cauthen, J. Gause and B. Song. Glyceollin Pathway Regulation in Response to Soybean Cyst Nematode. Presented at Plant Pathways Elucidation Project (P2EP) Symposium. North Carolina, 2017.

B. Phippen, A. Ivanina, I. Sokolova, J.D. Oliver. Jack of all trades, master of none: flexibility of pathogenic Vibrio species in a suffocating ocean. Queens University, Charlotte, NC. 

 

 PhD student publications and presentations (older)

Master's student publications and presentations (older).